- R&D capability
Based on the concept of developing green technology, YABEN chemical has long been committed to the accumulation and innovation of chiral and heterocyclic chemical synthesis processes and biological enzyme technology, and has independently developed a series of products including unnatural amino acids, heterocyclic aromatic templates, pharmaceuticals, pesticide intermediates, biocatalytic enzymes and so on. YABEN chemical's R & D sites include two R & D centers in Zhangjiang pharmaceutical Valley, adjacent to the R & D institutions of multinational pharmaceutical enterprises such as GSK, Roche and AstraZeneca in China, and the process development laboratory in Taicang base. The supporting GMP kilogram level laboratory and pilot plant can provide customers with process development and amplification services from gram level to kilogram level and even 100 kilogram level.
In addition, YABEN chemical has established a pharmaceutical intermediate R & D center in Songjiang, Shanghai, which was rated as the enterprise technology center of Songjiang District. Songjiang R & D center covers an area of 1000 square meters and has advanced analytical and testing instruments and intermediate synthesis laboratories. It can be engaged in route development, process research and development, pilot scale-up and quality standard research and development in the laboratory stage.
YABEN chemical also has a biological enzyme research and development center in Huzhou. The center has a group of senior experts in the research and development and utilization of biological enzyme technology, and a leading domestic biological enzyme laboratory. It has accumulated rich technical research and development and industrialization experience in enzyme gene cloning, expression, transformation, fermentation, separation and extraction, enzyme reaction and immobilization. In addition, YABEN chemical and Shanghai Institute of organic Sciences of Chinese Academy of Sciences jointly build a chiral compound development platform, which enables both parties to play a greater advantage in process development, resource sharing, raw material procurement, and industrialization.
|Experimental and analytical equipment
|Precision Electronic Balance
|Agilent HPLCs & GCs
|AB 4000 QTRAP® LC/MS/MS System
NMagritek Spinsolve NMR Spectrometer
|Radleys Parallel Reaction Stations
NMRRadleys Jacketed Lab Reactors 20L
|Corning Advanced-Flow Reactors G1 (AFR)
Corning Lab Reactor System (LRS)
|Differential Scanning Calorimetry(DSC)
Advanced Reactive System Screening Tool (ARSST)
|Mettler Toledo Electric Titration Apparatus
Mettler Toledo KF Titrators & Moisture Analyzers
- R & D Center
- R & D Center
- Shanghai Puyi Chemical Technology Co., LtdShanghai Puyi Chemical Technology Co., Ltd., located in Shanghai Songjiang Lingang science and Technology City, was established in 2008 and became a wholly-owned subsidiary of YABEN in 2016.
Puyi chemical is committed to providing safe and high-quality products and professional and reliable services for the global pharmaceutical industry and health care industry. At present, it is mainly engaged in the R & D and sales of raw materials, intermediates, amino acids, vitamins and other products, and provides customers with process R & D, product registration and production services from new product development to product listing.
The company has established good cooperative relations with many domestic research institutes and universities. It has a high-quality staff team, 60% of which are technical personnel in R & D and project management. It has built a chemical synthesis and Analysis Laboratory in Shanghai Songjiang Industrial Zone and an industrial biocatalysis laboratory in Huzhou City, Zhejiang Province.
- Shanghai YABEN Zhangjiang Innovation CenterThe administrative headquarters is located in Ningxia road, Putuo District, Shanghai, and the innovation center is located in Zhangjiang pharmaceutical Valley, Zhangjiang High Tech Park, Pudong New Area. It is mainly engaged in the research and development of advanced intermediates of anti-tumor drugs, anti nerve center drugs, cerebrovascular drugs and green plant protection products. The company has invested heavily in the purchase of R & D equipment and has become one of the most complete R & D equipment units in Shanghai Zhangjiang High Tech Park.YABEN chemical joined Shanghai R & D public service platform in 2014. On the one hand, YABEN chemical uses the scientific research institutions, instruments and facilities, scientific and technological documents, scientific research data and other scientific and technological innovation resources provided by the platform to serve the development of new technologies and products of the enterprise. On the other hand, YABEN Chemical shares a series of large-scale instruments and facilities to the platform to provide professional detection technology services for the vast number of scientific and technological innovation enterprises. The service objects include Fosun Pharmaceutical, Yangzijiang pharmaceutical, Huahai pharmaceutical, etc., with a total of more than 50 companies and nearly 10000 samples tested annually. It has won the "excellent service institution Award" and the "most popular online Award" issued by the platform for many times.
- Huzhou Yihui Biotechnology Co., LtdIt is located in the South Taihu science and technology innovation center in Huzhou City, Zhejiang Province. It is mainly engaged in the R & D and industrial application of enzymes for catalysis in medicine and fine chemicals. It has accumulated rich technical R & D and industrial experience in enzyme gene cloning, expression, transformation, fermentation, separation and extraction, enzyme reaction and immobilization.
Since its establishment in 2009, Yihui biology has developed and successfully industrialized dozens of pharmaceutical intermediate products, especially in non natural amino acids, chiral alcohols, chiral amines and other products. It won the first prize of Shanghai Science and Technology Progress Award in 2015. Through cooperation with Huzhou Industrial Biotechnology Center of Shanghai Institute of life sciences, Chinese Academy of Sciences, more than 1000 kinds of biocatalytic enzymes covering 78 categories have been developed and accumulated, forming an enzyme preparation library covering most enzymatic reactions other than general enzymes. These enzymes can be customized according to the needs of customers.